The Institute for Problems of Cryobiology and Cryomedicine in Kharkiv is one of the institutes of the National Academy of Science of Ukraine, and is the largest institute devoted to cryobiology research in the world. Established in 1972, the focus of the research is on cryoinjury, cryosurgery, cryopreservation, lyophilization and hypothermia. The Institute publishes the peer-reviewed scientific journal Problems of Cryobiology.